The Boyle County girls played on even terms with No. 23 Tates Creek for two-thirds of the game before falling 4-0 Wednesday at Lexington.
Tates Creek (3-3-2) scored all of its goals in the last 27 minutes as Boyle (4-4-1) ran out of steam.
"With their strength and speed, they just eventually wore us down," Boyle coach Brian Deem said. "I was extremely pleased with the way our girls played tonight."
Boyle goalkeeper Lydia Hignite logged 15 saves in the first half, when Tates Creek shot 18 times. She stopped three breakaway attempts.
"She just played an outstanding game," Deem said.
Central 3, Harrodsburg 0 - At Louisville, Central (4-3) scored twice in the first 10 minutes of the second half to break a scoreless tie and pull away from Harrodsburg (1-4).