His first one came just four plays after Waggener's Corey Thompson had stunned the Rebels by returning a short kickoff 65 yards for a touchdown to start the game.
"That wasn't good, but we also knew our offense and defense hadn't been on the field yet," Boyle senior tight end-linebacker Evan Teague said.
On Boyle's fourth play, Teague took a handoff, stopped and lofted a pass for Tamme, who had got behind Waggener standout Alfonso Smith. Tamme came back for the ball, got away from the defender and scored to tie the game.
"(Assistant) coach (Chris) Pardue told me to get ready for the fourth play," Teague said. "I took my gloves off after the third play, but I guess they really didn't notice. I just threw it out there and Seth did the rest. We had the same play open once earlier this season but I threw a wounded duck out there. This time it worked."
"Teams have been focusing on stopping our pass," the Boyle coach said. "We needed to do a few different things."
The Rebels (10-2) dominated the rest of the period. Quinn Givhan scored the first of his three touchdowns on an 8-yard run after a 23-yard reception by Tamme. The next series, Boyle quarterback Brandon Smith hit Tamme with a pass that he turned into a 57-yard score by again beating Alfonso Smith.
"He (Smith) was man-to-man on me. I told Brandon just to throw the ball and he did a great job of that," Tamme said.
Tamme's second touchdown catch enabled Brandon Smith to become just the 11th player in state history to reach 8,000 yards passing. He finished the game 10-for-14 passing for 202 yards and three scores to raise his career totals to 8,143 yards and 109 touchdowns.
"It's good to know I had a part in him getting 8,000 yards," Tamme said.
Rebels pull away at end of the half
Any chance Waggener (10-2) might have had to even stay close disappeared in the final two minutes of the first half after Brandon Smith made a rare mistake and threw a pass that was intercepted at the Waggener 8-yard line with Boyle leading 21-10.
Two quarterback sacks and a 20-yard punt gave Boyle the ball back at the 22-yard line. Givhan scored four plays later on a 2-yard run for a 28-10 lead with 2:05 left in the half.
The Rebels used three timeouts on defense and got the ball back on their own 40-yard line with 1:29 on the clock. Brandon Smith ran for 15 yards before completing three straight passes, including a 2-yard toss to Tamme for the score with 37.9 seconds left before halftime.
Waggener fumbled on its first play and a 22-yard pass to Evan Teague set up a 6-yard touchdown pass from Smith to Josh Miller with 21.3 seconds left to make it 42-10 at halftime.
"I didn't even realized we had scored so quick," Tamme said. "That was kind of amazing."
Chuck Smith thought it was all due to near perfect execution on both offense and defense.
"You can't end a half much better than that," the Boyle coach said. "I was pleased that we put the nail in the coffin when we had a chance. We used our timeouts wisely, played smart, got out of bounds and maximized all we could out of a little bit of time.
"We run the two-minute drill every day in practice, and we'll have a game where we will need that to win a game. But it sure helps to have a veteran quarterback running the offense, too."
A 46-yard pass to Tamme on the fourth play of the third quarter set up Givhan's 15-yard scoring run through the middle of Waggener's defense. Two plays later Waggener fumbled and Hagen Smith, who replaced injured Casey Brummett at safety in the second quarter, returned the ball 24 yards for the game's final touchdown.
For the second straight game, Boyle did not allow an opponent any passing yards. Waggener also managed to rush for just 105 yards, or seven less than Fairdale had the previous game.
"Our defense is getting better every week," Teague said. "They had a good running game, but we shut them down and that will help us next week."
Boyle will continue its quest for a sixth straight state title by hosting Central (10-2), a 47-14 winner over Bullitt East, in the regional title game this week.
"They are big and will throw the ball a lot more," Chuck Smith said. "Every game gets tougher, but we did a good job night containing their speed, and we just have to build on that and keep going."