The playoffs aren't a possibility, but a win would clinch a tie for second place with Trinity and DePauw in the Southern Collegiate Athletic Conference.
Frye said the biggest key to his team's late-season surge is the new spread offense has improved.
"The kids have developed and matured into our offense. We had to put a brand new offense in, and by the middle of the season, things clicked and the kids started to play well," Frye said. "The kids started understanding how it works and started executing it the way we wanted to."
Leading the charge for Centre have been a pair of freshmen, quarterback Tyler Osterman and running back Jonathan Pinque.
Osterman has completed 88 of 139 passes for 1,017 yards and nine scores, and has run for 244 yards and two scores.
Pinque scored twice in the win over Trinity and has 519 yards and 10 touchdowns on the season. He also has 24 catches for 259 yards and a score.
"Any time you get a freshman to contribute, it is always a surprise, and he's getting better," Frye said of his quarterback.
'There's going to be some good guys we have to replace'
But Centre will also see 11 seniors play their last game Saturday.
"It's a very small class, by far the smallest we'd recruited in the last 15 years. There's going to be some good guys we have to replace," Frye said.
Chief among them is senior linebacker Adam Hay, who Frye said "is one of the best linebackers I've ever coached." Hay has 102 tackles, including 10 for loss, with four sacks and two interceptions this year.
Senior Tyler Hinkel leads the Centre receivers with 24 catches for 358 yards and five touchdowns.
Colorado College is 0-8 overall and 0-6 in the SCAC, and is scoring just 11.4 points a game while giving up 34.6 points and 370.5 yards per game. But Frye said on film the Tigers haven't looked all bad.
"They're not a bad team. They should have beat DePauw (in a 37-34 loss Oct. 25.). They had DePauw on the ropes, and I'm not sure how they lost that game," Frye said. "If they would have won that game, I'm telling you their season would have been different. I'm a little anxious."
The altitude in Colorado Springs, Colo., which is 6,035 feet above sea level, is also an issue with Frye.
"It will be a tough transition for us. We're not going to get an opportunity to adjust to it," Frye said. "We get in late Friday night, and then we have to get up early and play at noon (Mountain Time),
"We're not really getting a chance to build up a sweat and practice through it. It takes us a quarter to kind of get adjusted to the altitude and play in that kind of environment. After a quarter, you are sucking air."
If Centre does get the win Saturday, Frye said it would be a big boost to end the season on a four-game winning streak.
"We turned a corner after Trinity," he said. "But now, let's not stop. Let's get some momentum as we turn the corner and move on."